Hormones & STDs: A Comprehensive Overview

Major Hormones: Origin and Function

Endocrine Glands and Hormones

HormoneGlandPhysiological Effects
ThyrotropinAnterior PituitaryControls the thyroid and stimulates thyroxine production.
AdrenocorticotropinAnterior PituitaryStimulates hormone production in the adrenal cortex.
SomatotropinAnterior PituitaryStimulates growth.
Follicle-Stimulating Hormone (FSH)Anterior PituitaryStimulates Graafian follicle formation in the ovary.
Luteinizing Hormone (LH)Anterior PituitaryRegulates testosterone and progesterone production.
Prolactin (LTH)Anterior PituitaryStimulates milk production.
OxytocinPosterior PituitaryStimulates uterine contractions during labor.
VasopressinPosterior PituitaryStimulates smooth muscle contractions and has antidiuretic effects.
ThyroxineThyroidControls metabolism. Deficiency causes goiter and cretinism; excess causes exophthalmos.
CalcitoninThyroidParathyroid hormone antagonist.
Parathyroid HormoneParathyroidRegulates calcium and phosphorus metabolism.
InsulinPancreas (Islets of Langerhans)Controls blood sugar concentration. Deficiency leads to diabetes.
GlucagonPancreas (Islets of Langerhans)Converts liver glycogen into glucose.
AldosteroneAdrenal CortexRegulates sodium and potassium metabolism.
CortisoneAdrenal CortexStimulates protein-carbohydrate conversion.
EpinephrineAdrenal MedullaControls responses to dangerous situations, stimulates heartbeat, and dilates pupils.
NorepinephrineAdrenal MedullaConstricts blood vessels.
TestosteroneTestesDevelopment of male sexual characteristics.
AndrosteroneTestesContributes to male secondary sexual characteristics.
EstradiolOvariesStimulates female sexual characteristics and influences female sexual behavior.
ProgesteroneOvariesRegulates the menstrual cycle, prepares the uterus for implantation, and prepares for breastfeeding.

Sexually Transmitted Diseases (STDs)

STDs are infections acquired through sexual contact with an infected person. The causes of STDs are bacteria, parasites, and viruses. There are over 20 types of STDs.

The Public Health Impact of STDs

  • An estimated 19 million new STD cases occur annually in the United States, with about half affecting young people aged 15-24.
  • STDs have a significant economic impact, with direct medical costs estimated at $15.9 billion annually.
  • Many STDs are asymptomatic, so many infected individuals are unaware of their status. Testing is crucial for diagnosis.

Causes of STD Transmission Among Teens

  • Increasingly early sexual activity.
  • Frequent partner changes.
  • Inconsistent condom or spermicide use.
  • Asymptomatic infections, leading to unknowingly spreading the disease.

Transmission

STDs are primarily transmitted through intimate contact with an infected person. While genital contact is most common, oral and anal sex can also transmit infections. Some STDs, like chancroid and crabs, can spread through self-contact. Others, like genital herpes, trichomoniasis, and vaginal candidiasis, can be acquired non-sexually. Gonorrhea, syphilis, and chlamydial infections can be transmitted from mother to child during pregnancy or childbirth, potentially causing severe congenital issues. While STDs initially affect the external genitalia, they can spread to the prostate, uterus, testicles, and other nearby organs. Many cause irritation, itching, and mild pain, but some, like gonorrhea and chlamydial urethritis, can cause female infertility.

Main STDs

DiseasePathogenEffects
Acquired Immunodeficiency Syndrome (AIDS)Human Immunodeficiency Virus (HIV)Weakens the immune system.
SyphilisTreponema pallidum (Spirochete)Causes chancres, generalized rash, and potentially lymphadenopathy and progressive paralysis.
GonorrheaNeisseria gonorrhoeae (Bacteria)Causes inflammation of the vaginal mucosa in women and urethral infection in men.
Genital HerpesHerpes Simplex Virus Type 2Causes fever and genital ulcerations.
ChancroidHaemophilus ducreyi (Bacteria)Causes painful genital ulcers.
Lymphogranuloma VenereumChlamydia trachomatis (Bacteria)Causes genital vesicles, fever, headache, and joint pain.
TrichomoniasisTrichomonas vaginalis (Protozoan)Causes itching, irritation, and discharge in women; can affect the prostate in men.
Vaginal CandidiasisCandida albicans (Fungus)Causes a white, itchy discharge.