Lipid Metabolism: Key Processes & Diseases

Lipid Metabolism

1. In the human body, synthesis of fatty acids occurs in:

c. Adipocytes

2. The critical process of emulsification of dietary lipids occurs:

b. In the duodenum

3. Cholesteryl esters are hydrolyzed by:

e. Answers C and D are correct

4. The role of bile in the digestion of triglycerides is:

a. Emulsification of fat drops to droplets

5. Beta-oxidation of very-long-chain fatty acids (VLCFA) occurs in:

e. There is no correct answer

6. Fatty acids are NOT:

c. Associated with proteins in membranes

7.

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Cardiovascular Health: Risk Factors, Diet, and Protein Metabolism

Cardiovascular Disease: Risk Factors and Prevention

Risk Factors for Cardiovascular Disease (CVD)

  • Hypertension
  • Age: Over 55 years for males, over 65 years for females
  • Diabetes
  • Increased LDL cholesterol (or low HDL cholesterol)
  • Estimated glomerular filtration rate below 60 mL/min
  • Family history of premature CVD
  • Obesity
  • Physical inactivity
  • Microalbuminuria
  • Snuff consumption (cigarettes)

Dietary Recommendations for Cardiovascular Risk Reduction

  • Balance calorie intake and physical activity to obtain and/or maintain
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Human Digestive System: Ingestion to Egestion

The Alimentary Canal

The alimentary canal is a long tube that forms part of the digestive system, along with the liver and pancreas. Key features include:

  • Peristalsis: The movement of muscles that contract and relax to propel food along the canal.
  • Sphincter Muscles: Specialized muscles that close off sections of the tube.
  • Mucus: A substance produced in goblet cells that helps food slide easily.

Ingestion

The process begins in the mouth with the teeth, lips, and tongue. Saliva plays a crucial role:

  • Water
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Understanding Different Diet Types and Their Applications

Normal Baseline Diet

Content: Daily average (g) Protein 110, Lipids 85, Carbohydrates 340. Dietary Fiber: 25g (Balanced); modest reduction in animal fats and salt, high fiber, high protein intake. Nutrient content exceeds the usual necessities.

Suitable for:

  • In its variant without soluble sugars, it is suitable for diabetic patients not requiring specific dietary restriction.
  • In the variant without salt, some canned food and industrial products that contain salt are removed.
  • In the variant with salt,
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Essential Vitamins: Functions, Sources, and Deficiencies

Vitamin D (Calciferol): D2-D6, derived from ergosterol and cholesterol via UV catalysis. Found in shells and leaves. Regulates calcium, preventing rickets and osteomalacia. Excess can cause digestive disorders and visceral calcification.

Vitamin E (Tocopherol): Found in green vegetables, seeds, oils, and eggs. Important for fertility. Deficiency leads to infertility, paralysis, and muscular dystrophy. Excess can be toxic.

Vitamin K (Phylloquinone): K1-K4, found in green vegetables and fish. K3 produced

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Nutrition in Pregnancy and Lactation: Key Factors

Nutrition During Pregnancy and Lactation

Background

  • Women’s nutrient needs increase during pregnancy (in the second and particularly the third trimester) and lactation.
  • Pregnant women require more protein, iron, iodine, vitamin A, folate, and other nutrients.
    • Deficiencies of certain nutrients are associated with maternal complications and death, fetal and newborn death, birth defects, and decreased physical and mental potential of the child.
  • Lactation places high demands on maternal stores of energy,
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