Microbiology Essentials: Disease Mechanisms and Host Defenses

Chapter 14: Microbial Interactions and Disease Patterns

Differentiating Key Microbiological Terms

  • Etiology/Pathogenesis: Etiology is the study of the cause of a disease, while pathogenesis describes the manner in which a disease develops.
  • Infection/Disease: Infection refers to the colonization of the body by microorganisms, whereas disease is any change in the state of health.

Understanding Symbiotic Relationships

  • Symbiosis: The living together of unlike organisms.
  • Commensalism: One organism benefits,
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Ecosystem Basics: Trophic Levels, Food Webs, and Cycles

Trophic Nutrition and Food Chains

What is Trophic Nutrition?

Trophic nutrition refers to the feeding process or alimentation.

What is a Food Chain?

A food chain describes the feeding relationships between different species.

Why Are Food Chains Not Linear?

Food chains are not linear because some species are consumed by multiple others, connecting with other networks and forming what is called a trophic web (or trophic mesh).

Understanding Trophic Levels

Trophic levels group species based on common food sources,

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Microbe Identification: LPRA, Salmonella, Candida, Haemophilus

Microbacterium Leprae (LPRA)

Identification: Microbacterium leprae causes LPRA (also known as Hansen’s disease). It is an intracellular, pleomorphic bacterium, usually shaped like a stick. It is acid and alcohol resistant, remotely related to Mycobacterium tuberculosis. Histological stains include Ziehl-Neelsen, Fite-Faraco, Munxar, and Sudan III.

Form of Transmission: LPRA is not very infectious. It is transmitted through droplets from the nose and mouth, in frequent and close contact with untreated

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Respiratory Diseases and Antibiotics: Causes, Treatment

General Medicine: Respiratory Diseases, Infections, and Antibacterial Agents

Introduction

General medicine covers a wide range of diseases and treatments, focusing on the diagnosis, prevention, and management of illnesses affecting different organ systems. Among the most common medical concerns are respiratory diseases, which affect the lungs and airways, often caused by infections. Infections can be viral, bacterial, fungal, or parasitic, and their treatment varies depending on the causative agent.

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Infectious Diseases: Bacterial, Viral, Fungal, and Parasitic Infections

Infectious Diseases

Skin Infections

  • Skin-Bac-Folliculitis: Caused by Staphylococcus infection, can spread to blood and organs.
  • Staphylococcal Scalded Skin Syndrome: Caused by Staphylococcus. Death is rare but can occur due to secondary infections. Common in infants; treated with antimicrobial drugs.
  • Impetigo (Pyoderma): Red face and limbs, caused mostly by Staphylococcus aureus. Hyaluronic acid and pyrogenic toxins are involved. Treated with oral and topical antimicrobial drugs.
  • Erysipelas: Infection
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Biotechnology, Immunity, and Bacterial Diseases: An Overview

Biotechnology: Obtaining Transgenics

To improve:

  • Productivity
  • Weather resistance [temperature]
  • Action against pathologies

Production: Recombinant DNA

Recombinant DNA [selected desirable gene incorporation] is inserted into an organism to improve it. Restricted bacterial enzymes [DNA sequence] cut the genes. Bacteria are isolated, copied, and then joined to the organism that is to be improved, creating a transgenic organism.

Techniques to Incorporate Macromolecules and Proteins

Projectile injection, diffusion,

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